BRCA1 and BRCA2 are well known Breast Cancer (BC) associated genes that has been discovered in 1990s and usually are tested to assess the individual BC risk. What we can learn about them? Both BReast CAncer (BRCA) genes are considered tumour suppressor genes because are involved in a cellular process that prevent cells transformation to cancerous cells. The BRCA1 and BRCA2 proteins participate in DNA repair, a natural process that occurs frequently in our cells nucleus more than we though, maintaining DNA integrity after DNA damage. Mutations in the BRCA1 and BRCA2 genes results in predisposition of BC and contributes to the risk of other types of cancer such as ovarian, prostate, pancreas, stomach and skin.
Currently it is well known that oral diseases are closely related to cardiovascular diseases.
People with poor oral health have a higher risk of suffering cardiovascular disease, and may increase the risk up to 25-50%.
Oral cancer is divided according to its location in: oral cavity (lips, cheeks, gums, tongue) and oropharynx (pharynx, tonsils and tongue base).
TellmeGen began with an aim to allow people easy access to genetic information. TellmeGen is a genetic test that helps you not only in the prevention of over 125 diseases, but slow down their development as well.
Oral diseases share common risk factors with systemic diseases, most associated with genetic factors and lifestyles, such as unhealthy diet, smoking, excessive alcohol consumption and poor oral hygiene.
Inflammatory bowel diseases (IBD), which commonly include Crohn’s disease and ulcerative colitis, are characterized by gastrointestinal symptoms, but they can also manifest in extraintestinal complications in up to 20% of cases, predominantly in the oral cavity and in the joints.
Osteoporosis is the result of a loss of bone mass and a change in bone structure.
Bone is a living tissue that is in a constant state of regeneration, what means that the body is able to eliminate the most damaged and weak cells that make up the bone, bone resorption process, and replace them with new cells that make up new tissue, bone formation process.
Diabetes mellitus (DM) is a chronic and multifactorial pathology characterized by the existence of hyperglycemia, an inevitable consequence of an absolute or relative insufficiency of insulin secretion and insensibility or resistance of tissues to the metabolic effect of insulin. Over time, the disease can cause damage, dysfunction and failure of various organs.
Many people wonder how much a DNA test cost and, it is normal, since it is a very new and innovative service. Let’s begin by reviewing a bit as the price of genetic analysis has been falling exponentially.
Today is my first time as a blogger. It’s a challenge for me, the same as this project is. Only a few days ago I was asked to write something for the blog; anything, it wasn’t important what as long as I thought it was interesting. But there are so many things that I think are interesting! I thought it would be difficult for me to choose a topic, begin to write….until I stumbled across an interview with María Blasco (researcher and director of the CNIO Cancer Center) and then I knew: I was going to write about women scientists!