Your genes don't decide your health, but they do influence it. Genetic vulnerability estimates the extent to which your genetics contribute to a specific trait or health condition. That trait, the phenotype, is the expression of your genotype (the information contained in your DNA) and is influenced, to a greater or lesser extent, by the environment and lifestyle.
Pharmacogenetics studies how your genetic variants influence your response to certain medications. When you take a drug, your body absorbs it and distributes it to its site of action, where it interacts with receptors and enzymes; then it metabolizes and eliminates it. Genetic variations can interfere in any of these stages. This explains why the same medication acts differently in each person: in some it is effective, in others it produces adverse effects, and in others it requires a different dose.
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