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Glioma

Glioma is refers to an ample category of tumors that occur in the brain and spinal cord and which arise from the supportive tissue of the brain, called glia, the principal brain cells that can produce tumors. The symptoms, prognosis and treatment of a malignant glioma depend on the age of the patient the exact type of tumor and its location in the brain. These tumors tend to grow or infiltrate in the normal brain tissue which makes surgical removal difficult or impossible and complicates treatment.

Symptoms

The symptoms of a glioma are similar to those of other malignant brain tumors and depend on the area of the brain affected. The most common symptom is a headache, which affects almost half of the patients with a cerebral tumor. Other symptoms can be seizures, memory loss, physical weakness, loss of muscle control, problems seeing or speaking, cognitive loss and personality changes. These symptoms may vary depending on the location of the tumor; they can also vary or change as the tumor grows and destroys the brain cells, compresses parts of the brain and causes swelling of the brain and pressure on the skull.

Prevention

The development of hereditary brain tumors cannot be foreseen, but excessive exposure to factors that can produce a mutation in the genes such as ionizing radiation therapy or certain chemical products, smoking, infections, radiation, immunosuppressive drugs can be prevented.

For cancer prevention, the antioxidants found in foods may be of some help. Coffee, which contains antioxidants and also caffeine, lessens the risk of having gliomas.

Gene or region studied

  • 7p11.2
  • 8q24.21
  • TERT
  • 4p15.2
  • CDKN2B-AS1
  • RTEL1
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