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Meningioma

Meningioma is a slow growing, generally benign (without the ability to (metastasize), tumor that develops in the meninges (the tissue covering the central nervous system, brain and spinal cord).

It represents 20% of all the primary cerebral tumors and is most frequently located in the lobes of the brain, although they can appear on the spinal cord. Only about 1% of the meningiomas become malignant.

Meningiomas appear in adults between the ages of 30 - 70 fundamentally and affect twice as many women as men. They are also more frequent in black races.

Symptoms

Meningiomas are usually slow growing and can reach considerable size before they interfere with the brain's normal functioning. The symptoms resulting from a meningioma depend on the location of the tumor within the brain. Headache and weakness in an arm or leg are the most common symptoms. However, the following symptoms may also occur.

  • Changes in vision, such as seeing double or blurriness
  • Headaches that worsen with time
  • Hearing loss
  • Memory loss
  • Loss of smell
  • Seizures
  • Weakness in your arms or legs
  • Sensorial changes: touch, vision, smell, or hearing problems
  • Changes in personality, mood, ability to focus, or behavior

It is important to note that these symptoms are not specific to this illness and that the majority of persons who have them do not have a meningioma.

Prevention

Careful observation is sometimes the best course of action for patients with meningioma. It seems that hereditary factors also play an important role in meningioma development, as well as environmental and hormonal factors which make the disease difficult to prevent. Thus, the best preventative measures are those that avoid or reduce risk factors.

Gene or region studied

  • C10orf114
  • 4p15.2
  • BRIP1
  • MTRR
  • MLLT10
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