PSA (Prostate-specific Antigen) Levels

Prostate-specific antigen (PSA) is a protein synthesized exclusively by the prostate gland. A small amount is found in the blood stream and serves for the diagnosis, prognosis and follow-up of prostate cancer and other prostate disorders such as prostatitis. PSA analysis has been widely used to detect prostate cancer in men. It is also used to monitor men who have been diagnosed with prostate cancer to check for reoccurrence after the initial treatment or if there is a reaction to the treatment.

The higher the concentration of PSA, the greater is the possibility that a man has prostate cancer or some other problem related with the prostate gland. Nonetheless there are other reasons for an elevated concentration of PSA without there being a malignant process. There can also be men with prostate cancer who do not have high concentrations of PSA.

The reference VALUES for PSA serum vary depending on the different laboratories although the normal accepted value at present is up to 2.5 ng/ml. Its production depends on the presence of androgens and the size of the prostate gland.

Gene or region studied

  • HNF1B
  • 10q11.23
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