Vitamin D levels
Vitamin D is an essential nutrient for the maintenance of our health. It is important to maintain optimal levels of vitamin D at all stages of our lives, as it is an essential nutrient for the development of important functions such as the formation and maintenance of bones, the absorption of other nutrients such as phosphorus and calcium, as well as the proper functioning of the immune system. In addition, vitamin D, together with calcium, contributes to the prevention of osteoporosis, a pathology that causes bones to become thinner and weaker, leading to the appearance of fractures. Finally, vitamin D is also involved in muscle movement and in the transmission of nerve impulses.
90% of the vitamin D in our body comes from sunlight and is generated from the photolysis of 7-dehydrocholesterol in the skin through the action of UVB (ultraviolet rays). In the absence of sun exposure, at least 1000 IU (preferably 2000 IU) of vitamin D/day would be required to meet the needs of an adult. To a lesser extent, vitamin D can also be obtained from food (especially high-fat fish) and through dietary supplements.
The functions of vitamin D include
- Maintenance of intracellular and extracellular calcium concentration.
- Increases intestinal absorption of calcium and phosphorus
- Stimulates bone resorption
- Promotes differentiation to osteoclasts
- Increases intestinal calcium transporter protein synthesis
- Increases renal reabsorption of calcium and phosphorus
- Acts on the immune system
- Inhibits proliferation and differentiation of keratinocytes in the skin
- Reduces plasma renin activity and levels of angiotensin II
Gene or region studied