Ancestry service, Traits and Wellness
Technology and laboratory
tellmeGen™
Laboratory
Our reference laboratory is Eurofins Genomics Denmark, the only one in Europe equipped to handle the high volume of samples we process monthly. We collaborate closely with them in both Microarray Chip analysis and whole genome sequencing (WGS). As a European leader in genetics, this laboratory holds top-tier certifications that guarantee excellence at every step: It is a reference laboratory in Europe with the following certifications:
ISO 17025: Accreditation for analytical excellence in laboratory testing.
ISO 13485: Compliance with standards for oligonucleotides in medical devices.
GLP: Gold Standard for Non-Clinical Safety Studies.
GCP: Pharmacogenomic Services in Clinical Studies.
cGMP: Production and testing aligned with pharmaceutical and biotechnological requirements.
Technology: Illumina Sequencing Platform (Microarray Chip)
At tellmeGen, we employ Illumina's sequencing platform, a technology of American origin with leading industry patents, which allows us to analyze over 750,000 genetic markers (SNPs) with exceptional precision. Furthermore, we personalize the analysis by incorporating over 10,000 additional SNPs to enhance specificity and utility in clinical and ancestry applications. To maximize reliability, we duplicate the analyzed probes, elevating the reproducibility and quality of results to the highest industry standards. This ensures detailed and reliable genetic information, ideal for informed decisions in health and well-being.
Broad applications in research and clinical practice
The selected variants optimize imputation with high accuracy for those with an allelic frequency above 1%. We include specific markers that deliver optimal results in health, personal traits, and ancestry, supported by the robustness of Illumina technology.
Global content
Our platform integrates a multi-ethnic backbone that covers the entire genome, with clinical research variants, quality control (QC) markers, and flexibility to incorporate additional content. This inclusive approach ensures relevance for users of diverse ethnic backgrounds.
High-performance workflow
Designed to process thousands of samples weekly in large-scale studies, our technology combines genetic expertise with computational power. This expands the analysis of a DNA chip to tens of millions of variants through imputation, allowing the study of associations with diseases not covered in the initial 750,000 SNPs. Thus, we estimate individual genetic risk with unprecedented accuracy.
Robust, high-quality essay
The tellmeGen chip, based on innovative Illumina technology, offers superior reproducibility of over 99%, ensuring consistent and reliable results in every analysis.
Technology: Whole Genome Sequencing (WGS)
Always at the forefront of genetic innovation, at tellmeGen we stay up-to-date with the most whole-genome sequencing technologies. With our most recent update, the tellmeGen Ultra WGS (30x), we analyze up to 3 billion genetic variants, far surpassing classical genotyping techniques, which are limited to a few million. This process not only focuses on SNPs but also detects other variants that often go unnoticed in conventional analyses, such as tandem repeats or structural rearrangements. To ensure maximum accuracy and reliability, we employ 30x coverage based on leading American technology and patents in the sector, meaning each nucleotide is read an average of 30 times, minimizing errors and confirming results with the highest possible accuracy.
Full reading of variants and structural alterations
Unlike other more restricted genetic analyses, tellmeGen Ultra WGS (30x) identifies and characterizes a wide range of genomic modifications, including SNPs, rare variants, copy number variants (CNV), large insertions/deletions, tandem repeats, and rearrangements. We understand the complexity of this data, which is why we offer you personalized support to interpret it. Additionally, you can opt for an additional report on variants of uncertain significance to further enrich your results and gain a complete overview.
Updated and constant results
The tellmeGen Ultra WGS (30x) includes the first year free of tellmeGen+, our annual subscription service that ensures the automatic incorporation of all new updates and functionalities to your results. This way, your genetic information evolves with us, continuously improving without any extra effort on your part.
A systematic and experienced job
With years of experience in the genetic industry, we collaborate with top-tier suppliers and experts to deliver results of excellence and optimal efficiency. This comprehensive approach is backed by American-sourced technology and innovative patents, ensuring that every step of the process meets the most rigorous standards of quality and precision.
Safe and reliable results
The tellmeGen Ultra WGS (30x) analysis features 30x coverage, which is equivalent to reviewing each nucleotide up to 30 times on average. Imagine reading a book where each letter is checked repeatedly: this reduces the margin of error to practically nonexistent levels, offering you results you can fully trust for informed decisions about your health and well-being.
