Height is the height of an individual from head to toe. It is a complex trait influenced by genetic and environmental factors. It is a characteristic that shows great heterogeneity and can vary according to age, sex, geographic region or ethnicity.
Height
Currently, the average height of women ranges between 1.50-1.70 meters, while in men it varies between 1.62-1.83 meters. Adults with the tallest average height in the world are found in Northern Europe, with an average of 1.80 meters for men and 1.70 meters for women.
Height is largely a genetic trait. It is estimated that 80% of an individual's height is determined by the genetics inherited from the parents. The genes responsible for height are distributed across multiple loci in the genome, making height a polygenic trait. Height inheritance follows a complex genetic pattern, in which both parents contribute to the trait, but not always equally. Although genes from both parents have an impact, the genetic influence on height follows a complex pattern, with the combination of multiple genetic variants affecting bone growth and physical development.
However, certain factors, especially during the growth phase, can influence final height, such as nutrition, certain illnesses, or the frequency of physical exercise. Environmental factors, such as adequate nutrition during childhood and adolescence, are also determinants in physical growth, although they do not have the same impact as genetic factors. In addition, studies indicate that the mother's nutrition during pregnancy is also a factor associated with the trait. This has been evidenced throughout history as the average height of populations has been highly variable, with periods of increase and decrease, the latter coinciding with social and economic problems of the time (famines, wars, diseases, etc.).
During aging, a slight reduction in height may occur. This is due to the decrease in intervertebral disc height, atrophy of soft tissues, osteoporosis, and/or postural changes associated with certain degenerative diseases.
Number of observed variants
13.5 million variants
Number of loci analyzed
1357 loci
Genes analyzed
Bibliography
UK Biobank Database. Standing height, Data-Field 50 [Version Feb-2022]
National Library of Medicine (NIH). Is height determined by genetics? [Jun 2020]
Grunauer M, Jorge AAL. Genetic short stature. Growth Horm IGF Res. 2018 Feb;38:29-33
Jelenkovic A, et al. Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts. Sci Rep. 2016 Jun 23;6:28496.
