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Food intake control

There is a worldwide epidemic of obesity across all age groups, it is estimated more than 50% of the global population will be overweight or obese by 2030.  Being overweight is a known risk factor for many chronic diseases, such as type 2 diabetes, hypertension, and cardiovascular events. Increasing food intake is an important contributor to the obesity epidemic among other factors such as age, sex, physical activity, alcohol and smoking.

There are several genes that have been related to obesity and energy intake. Most of them seem to participate in the feeding control like for example LEPR (leptin receptor gene), NP-Y (neuropeptide-Y gene), MC4R (melanocortin 4 receptor gene), ANKK1 (kinase domain containing 1 gene) and FTO (fat mass and obesity–associated gene).

Gene or region studied

  • NPY
  • MC4R
  • ANKK1
  • FTO
  • LEPR
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