Desipramine (Dosage)
Desipramine belongs to a class of medications called tricyclic antidepressants (TCAs). It acts by raising the concentrations of certain natural substances in the brain that are necessary for mental balance.
The most common side effects of taking desipramine are nausea, drowsiness, weakness or tiredness, nightmares, dry mouth, sun sensitivity, changes in appetite or weight, constipation, urinating difficulty or frequent urination and changes in sexual desire or ability. Less commonly, the following adverse effects may occur: muscle spasms in the jaw, neck, and back, slow or difficult speech, shaking or uncontrollable movement of any part of the body, fever, severe rash, yellowing of the skin or eyes, seizures and sore throat, fever and other signs of infection.
BRAND NAMES
- Norpramin®
- Pertofrane®
Bibliography
Hicks JK, Sangkuhl K, Swen JJ, et al.Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update. Clin Pharmacol Ther. 2017 Jul;102(1):37-44.
Samer CF, Lorenzini KI, Rollason V, et al.Applications of CYP450 testing in the clinical setting. Mol Diagn Ther. 2013 Jun;17(3):165-84.