Technology and laboratory
Technology: Illumina Global Screening Array
At tellmeGen, we use the latest Illumina Microarray technology, which allows us to obtain information from more than 750,000 SNPs. We perform the customization of said Array, with more than 10,000 SNPs for research, and to increase the specificity and usefulness in clinical practice and on Ancestry. Also, we duplicate the probes interpreted to increase the reliability of the information provided to the highest standards of quality and reproducibility in the industry.
Wide applications in research and clinical practice
The variants included have been selected to allow us to obtain high imputation accuracy, specifically for variants with allelic frequency above 1%. In addition, specific variants have been included to allow us to achieve the best results related to both health and ancestry.
It includes a multiethnic spine of the entire genome, with the design of clinical research variants, quality control (QC) markers and the flexibility to add content.
Supports high throughput processing of thousands of samples per week for population-scale studies. At tellmeGen we apply the combination of genetic knowledge and computational power to significantly increase the number of variants analyzable with a DNA chip to tens of millions. This imputation analysis allows us to be able to study variants that have been associated with diseases and that were not present in the initial 750,000 variants. This achieves our goal of estimating the genetic risk of each individual more accurately than ever before.
Robust, high-quality test
The chip used by tellmeGen features a technology that allows a reproducibility > 99%.
Our reference laboratory is Eurofins Genomics Denmark, the only laboratory in Europe capable of processing the high number of samples that we receive and process on a monthly basis. It is a reference laboratory in Europe with the following certifications:
- ISO 17025: Accredited analytical excellence
- ISO 13485: Oligonucleotides according to medical devices standard
- GLP: The gold standard to conduct non-clinical safety studies
- GCP: Pharmacogenomic services for clinical studies
- cGMP: Products and testing according to pharma and biotech requirements