Intestinal malabsorption results in insufficient absorption of sugars, fats, proteins and vitamins from food. It is generally associated with intestinal damage caused by multiple pathologies or other factors.
Non-celiac intestinal malabsorption
Intestinal malabsorption can be caused by a large number of pathologies such as celiac disease, Crohn's disease, chronic liver disease, pernicious anemia, chronic pancreatitis, cholestasis, cystic fibrosis, etc.
Intestinal malabsorption can also be caused by infections (bacteria, viruses and protozoa), surgical interventions (such as gastric bypass and gastrectomy), intolerances (lactose intolerance), food allergies, certain drugs and alcohol consumption.
Symptoms
In children it may cause retarded growth and development. In adults, it may cause loss of weight and muscle mass, weakness and cognitive problems. There are also frequent digestive alterations such as:
- Abdominal distention
- Colic
- Gas
- Chronic diarrhea (not present in all cases)
- Greasy stools (steatorrhea)
Prevention
There are no specific recommendations to prevent intestinal malabsorption and treatment will vary depending on the patient's possible pathologies that may be associated with intestinal malabsorption.
Number of observed variants
13.5 million variants
Number of loci analyzed
14 loci
Genes analyzed
Bibliography
Semrad CE. Approach to the Patient with Diarrhea and Malabsorption. Goldman's Cecil Medicine. 2012:895-913.
Intestinal malabsorption (non-celiac) UK Biobank Database. Data-Field 557 [Version 2018].
