Alkaline phosphatase levels

Alkaline phosphatase (ALP) is an enzyme found in various tissues of the body, with particularly high concentrations in the liver, bile ducts, bones, kidneys and intestine. This enzyme plays an important role in numerous physiological processes, including bone and liver metabolism.

ALP levels are measured by a blood test. Normal values may vary according to age, sex and the laboratory method used, but values between 44 and 147 IU/L in adults are generally considered normal. ALP levels may be higher in children and adolescents due to bone growth, as well as in pregnant women.

Alkaline phosphatase has essential functions in bone, it is produced by cells called osteoblasts which are crucial for bone growth and repair of bone breaks. It is also a relevant enzyme in the liver involved in the transport of molecules in hepatocyte membranes and in bile secretion.