Resting heart rate

The resting heart rate is the rate at which the required amount of blood is pumped without any physical exercise. Normal values range from 50 to 100 beats per minute. It is a trait significantly influenced by genetics and correlated with life expectancy.

Heart rate (HR) is the number of times the heart contracts during a unit of time, usually one minute. For the body to function properly, the heart must pump blood at a certain rate and pressure. This rate can be determined at rest or in response to activity, depending on clinical interest.

The resting heart rate is the one that occurs in the absence of movement and for its determination the person must be seated or lying down and not have practiced physical activity just before. There is a wide range of normality, with normal levels between 50 and 100 beats per minute, depending on the individual. Resting heart rate is influenced by genetic factors, physical and psychological state, environmental conditions, posture, body size, medications, age and gender.

Generally, a lower resting HR indicates more efficient cardiac function and better cardiovascular fitness. For example, it is common for well-trained athletes to have a resting heart rate of less than 50. However, an unusually low (bradycardia) or high (tachycardia) resting HR may indicate a health problem, so it is important to consult your physician in either situation.

Number of observed variants

13.5 million variants

Number of risk loci

74 loci

Genes analyzed

ACHE ADCK1 ALG10B APOC1 ARHGAP10 ARHGEF40 B3GNT7 BCL11A CACNA1C CALCRL CCDC141 CD34 CD46 CDC23 CDH11 CDH2 CDH6 CHRM2 CPNE5 CSKMT DCP1A DGLUCY DPF3 EPPK1 FBXL17 FLRT2 FRMD4B GAREM1 GCKR GJA1 GMPPB GNB4 GNG11 GPATCH2 HCN4 KCNJ5 KIAA1755 KLHL42 LMO4 MAPKAP1 MEF2D MET MFF MICAL2 MIX23 MYH11 MYH6 NKX2-5 PDE3A PLD3 PLN PMP22 PPARGC1A PPFIA2 RASSF3 RNF220 SCN10A SCN5A SGIP1 SLC35F1 SOX5 SPAAR SPEG SREBF1 SUN2 SYT10 TBX20 TMEM258 TP53I11 TTN WIPF1 ZHX3 ZNF800

Bibliography

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