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Progressive supranuclear palsy

Progressive supranuclear palsy (PSP) is a rare brain disorder that causes serious and permanent problems with control of gait and balance, along with complex eye movement and thinking problems. It is not frequent (20 times less common than Parkinson’s disease, a principal degenerative movement disorder) and affects elderly persons, especially men.

It is known that the symptoms of PSP are caused by the progressive deterioration of some of the brain neurons that control movement, similar to what happens in Parkinson’s, the similarity of which makes it difficult to diagnose. What is not completely known is what makes these brain cells degenerate.

PSP worsens progressively, and although in itself is not life-threatening, it does predispose the patient to serious complications such as pneumonia, difficulties swallowing, falls and fractures. With good attention to medical and nutritional needs, it is possible for individuals with PSP to live a decade or more after the first symptoms of the disease and many patients live to past 70 years of age.


  • MAPT