Ankylosing spondylitis (AS)
Ankylosing spondylitis (AS) is a chronic inflammatory disease that fundamentally affects the vertebrae in the spine causing it to fuse together and making the spine less flexible. More men (between the ages of 20-30) than women are affected.
Ankylosing spondylitis belongs to the family of spondyloarthropathies (SpA), a heterogeneous group of rheumatic illnesses interrelated in clinical, genetic, radiographic alterations and treatment. Although the exact cause of the disease is unknown, it is known that genetics plays a part in its development and that there is an increased risk for those persons who have a family history of the disease.
GENE OR REGION STUDIED