Acetylsalicylic Acid (ASA) (Efficacy)

Acetylsalicylic acid is used as an analgesic, anti-inflammatory, antipyretic and antithrombotic. Its antithrombotic effect could be related to the presence of the PI A2 polymorphism, associated with greater thrombin generation and lesser effect of ASA.

Aspirin, the ester acetylsalicylic acid (ASA) was clinically introduced in 1899 as an analgesic, anti-inflammatory, antipyretic and anti-thrombotic. Once in the organism, acetylsalicylic acid is hydrolyzed to salicylate which is also active.

The analgesic and anti-inflammatory properties of acetylsalicylic acid are similar to those of other non steroid anti-inflammatories. Aspirin is used to treat numerous autoimmune and inflammatory reactions such as juvenile arthritis, rheumatoid arthritis and osteoarthritis. Because of its anti-thrombotic properties, it is used to prevent or reduce the risk of heart attack and transitory ischemic attacks. During the greater part of the 20th Century, aspirin was used as an analgesic and anti-inflammatory, but after 1980 its capacity to inhibit blood clotting was proven, promoting its widespread use as a preventive treatment for heart attacks and strokes.


  • ADIRO®
  • A.A.S. ®


Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

  • hives
  • rash
  • swelling of the eyes, face, lips, tongue, or throat
  • wheezing or difficulty breathing
  • hoarseness
  • fast heartbeat
  • fast breathing
  • cold, clammy skin
  • ringing in the ears
  • loss of hearing
  • bloody vomit
  • vomit that looks like coffee grounds
  • bright red blood in stools
  • black or tarry stools

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