Gefitinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase with activity in non-small-cell lung cancer. It works by blocking the action of tyrosine kinase to stop growth, inhibits the apoptosis, the production of proangiogenic factors and the s metastatic spread. By blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply, it helps to stop the cancer from growing and spreading.;
It is used in the treatment of locally advanced or metastatic non- small cell cancer with EGFR-TK activating mutations.