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Adjuvant chemotherapy in primary breast cancer. Trastuzumab (Herceptin)

Trastuzumab belongs to the class of medications called monoclonal antibodies.

This monoclonal antibody interferes with the receptor 2 of the human epidermal growth factor (HER2) which over-expresses in 20 -30% of the primary breast cancers and is associated with a worse prognosis.

This drug proves effective on some occasions.

Trastuzumab is also used with other medications to treat certain types of stomach cancer (HER2+) that have spread to other parts of the body (metastatic).

  • Herceptin®

Gene or region studied

  • FGFR4
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