*Reports on Genetic Vulnerability to Health Conditions and Hereditary Conditions from tellmeGen The tellmeGen Advanced genetic analysis includes reports on vulnerability to health conditions and hereditary conditions. The Advanced genetic analysis uses qualitative genotyping to detect clinically relevant variants in genomic DNA from saliva to report on genetic vulnerability and carrier status. Although useful, the information is not intended to diagnose any disease. Ethnicity may affect the relevance of each report and how genetic vulnerability results are interpreted. Each genetic vulnerability report describes whether a person has variants associated with an increased vulnerability to developing a disease but does not describe the total risk of developing the disease. The test is not intended to report on current health status or to make medical decisions, including medication or treatment. Hereditary condition reports can determine if a person is a carrier of a genetic variant but not if they have two copies of any genetic variant. These reports are not intended to inform future disease risk, fetal health, or the risk of diseases in a newborn child. Warnings and Limitations: The tellmeGen genetic vulnerability report for BRCA1/BRCA2 informs about 832 variants in the BRCA1 and BRCA2 genes. The report describes whether a person’s genetic result is associated with increased vulnerability to developing breast and ovarian cancer and may be associated with higher vulnerability to prostate, pancreatic, and other cancers. The included variants do not represent all BRCA1/BRCA2 variants in individuals of most ethnicities. This report does not include variants in other genes related to hereditary cancers, and the absence of variants does not rule out the presence of other genetic variants that may impact cancer risk. This report is for informational purposes without medical prescription and provides genetic information to discuss with a healthcare professional. Results should be confirmed in a clinical setting before taking any medical action. **Pharmacogenetics Reports from tellmeGen The tellmeGen Advanced genetic analysis uses qualitative genotyping to detect variants in multiple genes in adult genomic DNA from saliva to report on the processing of certain medications and facilitate discussions with a healthcare professional. It does not describe whether a person will or will not respond to a specific drug. Our pharmacogenetics report provides information on variants associated with the metabolism of some drugs and on the potential effect of therapies with certain medications. Results should be confirmed by an independent genetic test prescribed by your healthcare provider before taking any medical action.Warning: The information from the Advanced analysis should not be used to initiate, stop, or change any treatment and does not analyze all possible variants that may affect metabolism or protein function. The tellmeGen Advanced genetic analysis does not substitute for a visit to a healthcare professional. Changing your current treatment can lead to harmful side effects or reduce the expected benefits of your medication, so consult your healthcare professional before taking any medical action.

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